PRRT2 and synovial sarcoma: Specific inhibition of ROCK2 or p38 MAPK blocked LPA-induced IL-17 mRNA expression, but inhibition of PKC did not affect LPA-induced IL-17 mRNA expression, indicating that LPA-induced IL-17 expression may be mediated by ROCK2 and p38 MAPK signaling pathways in our mouse model of SS.