DHTKD1 and neoplasm: Figure 1B–1E show that tumor cell lines (NCI-H508, Huh7, A549, and SiHa) infected with AdC7-SP/E1A-ΔE3 exhibited significant increases in E1A expression relative to counterparts infected with AdC7-ΔE1-ΔE3 (p < 0.0001).