The MDA5 antibody, also known as an anti-CADM-140 antibody, has especially been associated with CADM [6], and has been used to detect dermatopulmonary syndrome in patients who have undergone allogeneic hematopoietic stem cell transplantation [9] or in patients with DM [10, 11]. The gene discussed is IFIH1; the disease is clinically amyopathic dermatomyositis.