To address if high expression of anti-apoptotic proteins contributes to the aggressive phenotype in IBC, we evaluated the expression of XIAP and NFκB, key pro-survival factors, in tumor emboli present in untreated IBC patient tumor samples made available through the World IBC Consortium from a total of 14 samples with documented tumor emboli as described in methods. The gene discussed is XIAP; the disease is inflammatory breast carcinoma.