Other common genomic abnormalities found were a relative copy number loss of TP53 and APC as well as a number of inactivating mutations on tumor suppressors such as APC-R216X, APC-K1444fs, CDKN1B-P137fs and TP53-L111R (Figure 3 and Supplementary Table 2). The gene discussed is TP53; the disease is neoplasm.