IFT81 and Complex Cyst of Kidney: It has been reported that ift81 mutant zebrafish embryos exhibit ciliary defects including spine curvature and kidney cyst formation.34 To first assess whether this p.L164P missense variant affects IFT81 protein expression, we performed a Western blot on zebrafish embryos injected with wild-type or mutant IFT81 mRNA.