In muscle, both GLUT1 and GLUT4 were considerably diminished (decrease of 27% and 31%, p<0.05 and p<0.01 respectively) by kidney disease, and GLUT1 and GLUT4 were inversely affected by CKD in adipose tissue as compared to the muscle (increase of 27% and 106%, N.S. and p<0.01 respectively). The gene discussed is SLC2A4; the disease is chronic kidney disease.