To examine whether the modulation of B cell responses in LTBI/Ss co-infection is reversible following anthelmintic therapy, we measured the levels of Mtb–specific IgM and IgG, the circulating levels of BAFF and APRIL and the numbers of various B cell subsets in LTBI/Ss individuals six months following anthelmintic treatment. Here, TNFSF13B is linked to coinfection.