SUV39H1 and posterior cortical atrophy: Using C4-2B cells, we generated two PCa cell lines with stable overexpression of different size SUV39H1, one is the full-length SUV39H1 (SUV) comprising 412 aa and another one is a C-terminally truncated SUV39H1 comprising 243 aa without the SET domain (ΔSET) (Figures 2a–c).