Turoctocog alfa pegol (N8-GP, Novo Nordisk A/S, Måløv, Denmark) is a novel, glycoPEGylated, extended half-life rFVIII product in development for the prophylaxis and treatment of bleeding episodes in patients with hemophilia A. Attachment of a 40 kDa branched polyethylene glycol (PEG) molecule to rFVIII extends the half-life so that higher trough levels of native FVIII are available to provide safe and effective prophylaxis. This evidence concerns the gene F8 and hemophilia A.