TP53 and Parkinsonism: In addition, results from a recent study in a Parkinson's mouse model showed that PFT-μ prevents 1-methyl-4-phenyl-1, 2, 3, 6-thetrahydropyridine (MPTP)-induced neurotoxicity by inhibiting mitochondrial p53/Bcl-XL interactions, impaired mitochondrial transmembrane potential, and cytosolic cytochrome c release (Shin et al., 2016).