NEUROG3 and pancreatic insulinoma: WT Ngn3 also migrates more slowly than 6S-A Ngn3 in MIN6 cells, derived from the islet cancer insulinoma (Ishihara et al., 1993), as well as in mPAC cells derived from pancreatic ductal adenocarcinoma (Yoshida and Hanahan, 1994) (Figure 1D).