LIPC and atherosclerosis: The ANXA2-R1 rs17845226 SNP has modest LD (r2 ≥ 0.4) with 34 SNPs, all located downstream of the ANXA2 gene-coding region in the long intergenic region between two genes, FOXB and ANXA2 on chromosome 15, and near the RORA and LIPC loci, which play roles in lipid metabolism and atherosclerosis (Supplementary Fig. 2).