Due to the complex and dynamic nature of EMT and MET, multiple signaling pathways that are important for both normal development and cancer development, including TGF-β, Wnt/β-catenin, Notch, EGF, HGF, FGF, and HIF, have been implicated in the regulation of these processes [6, 8, 12]. The gene discussed is TGFB1; the disease is cancer.