In addition, Matsumoto et al. [9] and Kamada et al. [10] developed a lectin-enzyme linked immunosorbent assay (ELISA) kit using Lewis- and core-type fucose-binding AAL, and showed that AAL reactive-fucosylated haptoglobin (AAL-HP) might represent a potential biomarker for PC. Here, HP is linked to pachyonychia congenita.