Spada et al. 24 reported increased expression of MICA in kidneys of patients with lupus nephritis and of Rae-1γ and Mult-1 expression in the MRL/lpr lupus mouse model; however, they detected the expression of these NKG2DLs by immunohistochemistry assay and thus could only locate the NKG2DL expression in the glomerular cells in general, but not in any specific cell subset. Here, MICA is linked to lupus nephritis.