MICA and systemic lupus erythematosus: Indeed, increased serum level of soluble (s)MICA and extensive expression of MICA in kidneys of patients with lupus nephritis have been implicated in lupus pathogenesis23, 24, and expression of the other NKG2DL, ULBP, has been detected in hair follicle dermal sheath in alopecia areata25, 26; however, whether NKG2DLs are expressed on T cells in SLE is not known.