Notably, we found that the induction of the NKG2DLs ULBP1-3 expression was specific for SLE serum, since serum from patients with Sjogren syndrome, systemic scleroderma or rheumatoid arthritis did not induce the expression of NKG2DLs on Treg cells (Fig. 3A). This evidence concerns the gene ULBP1 and systemic lupus erythematosus.