Accordingly to the double stimulation (by Rottlerin and infection-induced ER stress and Rottlerin-inhibited mTORC1), we observed an exacerbated autophagic response, both at the microscopic (TEM) and the biochemical (Western blotting of LC3I/II and p62) level, in infected cells after Rottlerin exposure. This evidence concerns the gene SQSTM1 and infection.