Therefore, here we analyzed the expression of RIP1, pSer227-RIP3, RIP3 and cytotoxic phosphorylated forms of MLKL (pThr357-MLKL and pSer358-MLKL) in human myocardium from end-stage HF patients due to cardiomyopathy post myocardial infarction (CAD) and dilated cardiomyopathy (DCM). The gene discussed is MLKL; the disease is dilated cardiomyopathy.