In order to further analyse the role of stress-mediated MAPK or TLR signalling and oxidative stress in mistletoe-mediated apoptosis of Ewing sarcoma cells, TC-71 cells were treated with viscumTT, viscum or TT for 24 h in the absence or presence of the SB203580 MAPK14 inhibitor, the SP600125 MAPK8 inhibitor, the LPS-RS TLR4 inhibitor or the antioxidant NAC. Here, MAPK8 is linked to Ewing sarcoma.