IGF1 and neoplasm: To further investigate the role of KLF17 in the invasiveness of lung adenocarcinoma, we analyzed the expression of invasion-related tumor-cell genes, including MMP2, ERK1/2, TGFβ1, NFκBp65, VEGFA, TWIST, Id1, IGF-1, IL1RL1, TERT, RHOC, ADAMTS1, PKLR and uPA [33], between the KLF17-overexpression group and the control or parental groups.