Among them, Cornu Cervi Pantotrichum (Lu Rong), belonging to the tonic herbs, act on 5 AML-related SL gene pairs (including the 2 high confidence pairs) i.e., BRCA1-TP53 (0.82046875), CHEK1-TP53 (0.85), PNKP-PTPN6 (0.56), ATM-TP53 (0.56) and FLT3-MAPK8 (0.56), while Panax ginseng (Ren Shen) works on 4 of them (except for PNKP-PTPN6). This evidence concerns the gene MAPK8 and acute myeloid leukemia.