Ahypothesis-free look-up in MR-base of all available traits and outcomes identifiedassociations of rs492602:A > G FUT2 genotype with Crohn’s disease,cholesterol levels, inflammatory bowel disease and type 1 diabetes, but no associations forrs1047781:A > T FUT2 genotype, the SNP on which our findings are based.A future study could combine multiple genetic variants to proxy for vitamin B12in order to overcome pleiotropy. This evidence concerns the gene FUT2 and Crohn disease.