IL1B and gastric cancer: For instance, El-Omar EM et al[64] said that the polymorphisms of IL-1B-511T and IL-1B-31C alleles are significantly associated with H. pylori related diseases and the clinical presentations in a Caucasian research, they also concluded that IL-1B-31T allele is the wild type and the IL-1B-31C allele is a mutant, but Chang et al[65] said that mucosal IL-1β levels in H. pylori-infected GC patients were higher in patients homozygous for IL-1B-31T compared with IL-1B-31C/T and IL-1B-31C/C.