IL1B and gastric cancer: Another recent and new research investigated that H. pylori infection reinforces the relation between IL-1β-511 T allele with susceptibility to gastric cancer[OR = 2.04, 95%CI = 1.15–3.62 for recessive model], which means H. pylori infection as a risk factor might have synergistic effect with IL-1B-511T allele the development of GC[28].However, it exists a high Heterogeneity[P<0.0001, I2 = 84%].