Western blot analysis showed that only the synergistic combination of everolimus plus AZA significantly increased Bax with a concomitant decrease in Bcl2 expression, while there was no significant change in the expression of these proteins after the exposure of MZ‐CRC‐1 cells to everolimus or AZA alone (Fig. 8). The gene discussed is BCL2; the disease is colorectal carcinoma.