TNF and metabolic dysfunction-associated steatotic liver disease: In this context, the study of the effect of HT supplementation (10 mg/kg/d) in rats with non-alcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD) for 5 weeks showed increased levels of peroxisome proliferator-activated receptor-α (PPAR-α) and reduced expression of TNF-α and IL-6, thus confirming its anti-inflammatory properties [42].