As pointed out by Stegh [9], “confirming important roles of p53 in cancer suppression, these studies showed that reactivation of p53 in established tumors can temporarily stop tumor growth; the precise cellular mechanism is cancer type-specific, as lymphomas die by apoptosis, whereas p53 restoration in sarcomas and liver carcinomas leads to growth arrest and senescence. This evidence concerns the gene TP53 and sarcoma.