Of all parameters shown in Table 1 or reported in the results section, 6 were found to be independent prognostic factors for survival after radiotherapy in multivariate Cox regression analysis: absence of extra-skeletal metastases (p=0.0001), no pleural metastases/effusion (p=0.0001), CRP <5 mg/l (p=0.0001), positive oestrogen receptor (p=0.001), no lung metastases (p=0.001), no need for blood transfusion because of anaemia (p=0.048). This evidence concerns the gene CRP and anemia (phenotype).