44. Notably, both Kaplan–Meier and Cox regression analyses disclosed that ID4 methylation was an independent prognostic biomarker in patients with CN‐AML. Besides this, ID4 methylation could also act as a promising predictor in disease surveillance in patients with AML. These results together suggested that ID4 methylation might play a more crucial role in AML. The gene discussed is ID4; the disease is acute myeloid leukemia.