Increased levels of ALT, AST, and alkaline phosphatase were documented in respectively 9.5%, 9.8% and 9.1% of overweight subjects, and 16.9%, 14.9% and 10.8% of obese individuals.20 The first survey of the CASPIAN study revealed that those children with hypertriglyceridemic waist phenotype were more likely to have cardiovascular risk factors, especially overweight and hypercholesterolemia.23 This evidence concerns the gene GPT and Hypercholesterolemia.