In the case of atopic dermatitis, CRD showed that allergens which were only found in mite bodies (i.e., Der p 10, 11, 14 and Der p 18) were more often recognized by HDM allergic patients with atopic dermatitis than by patients with respiratory symptoms, whereas no difference in the frequency of IgE reactivity was found to allergens derived from faeces (i.e., Der p 1, 2, 5, 7, 21 and Der p 23) between patients with atopic dermatitis and patients with respiratory allergy [185]. The gene discussed is IGHE; the disease is atopic eczema.