CTSB and infection: Attempts to characterize the schisis fluid has been earlier carried out by Drenser and colleagues using SDS-PAGE and HPLC analysis, wherein two unique proteins were identified viz., Cystatin C and Tenasin C. Cystatin C is a cysteine protease inhibitor activated during infection and inflammation, while Tenasin C is an extracellular matrix glycoprotein, induced during tumorgenesis, inflammation or infection [6, 9].