Transfection with HSP70 in AM of TB patients to overexpress HSP70 (increased by 1.9-fold expression) significantly inhibited basal generation of TNF-α (603.7 ± 119.3 pg/ml, n = 10, p < 0.01) (Fig. 5A) by 57.4%, and IL-6 (209.8 ± 38.4 pg/ml, n = 10, p < 0.01) by 52.9%, but not normal subjects (Fig. 5B). This evidence concerns the gene TNF and tuberculosis.