For the heat map with the immunity-related genes, we included genes from the four known immune signaling pathways [Immune Deficiency (IMD), Janus Kinase and Signal Transducer and Activator of Transcription (JAK/STAT), cJun- N-terminal Kinase (JNK), and Toll], genes involved in cellular immune responses and hematopoiesis, immune-induced molecules, genes with immune receptor activity, and genes with general immune functions, which also included genes with putative immune roles (Figure 4A). This evidence concerns the gene TLR4 and Immunodeficiency.