Here, by screening 13 miRNAs that could predicatively bind the 3’UTR of ALDH1A1 for RISC-mediated degradation, we found that miR-23b accordantly exhibits lower expression in sphere cells derived from four cervical cancer cell lines (Hela, CaSki, C33A and Siha), indicating the downregulation of miR-23b is generally observed in cervical cancer stem cells (CCSCs). Here, ALDH1A1 is linked to cervical carcinoma.