The PET/CT images (representative images shown in Fig 1) at 144 hours post injection of 89Zr-GSK2849330 (0.5 mg/kg) showed low uptake in HER3-negative MIA-PaCa-2 tumors (group1) compared to HER3-positive CHL-1 tumors (group 2) and CHL-1 tumors in mice pre-treated with a high (50 mg/kg) non-labeled dose of GSK2849330 (group 3). Here, ERBB3 is linked to classic Hodgkin lymphoma.