However, we also noted that a SNP (rs6542095) near IL1A (the most significantly associated gene from our gene-based analysis) was found to be associated near GWS with endometriosis (P=3.45 × 10−7) and at GWS with moderate-to-severe endometriosis (P=3.43 × 10−8)28. The gene discussed is IL1A; the disease is endometriosis.