CD4 and cancer: We additionally compared the αSMA or Collagen-I content adjacent to cancer cells with or without each of the remaining pericellular T-cell subpopulations and noted that all T cells combined, CD4+ Teffs, Tregs and other T-cell subpopulations were found adjacent to cancer cells associated with higher levels of either αSMA or Collagen-I (Fig. 6g–n).