Patients with CRPCa and IGF-1R staining scores of 0–4, i.e. scores below median showed shorter cancer-specific survival than patients with staining scores of 6 and above; median survival was 2.5 versus 9.3 months (log-rank 11, P = 0.001, n = 15 vs. 32, Fig. 2f). This evidence concerns the gene IGF1R and cancer.