SCARB2 and infection: We compared the sequences of mouse and human SCARB2 (Fig. 3A) and highlighted the apical domains on the top of the SCARB2 molecules (Fig. 3A and 3B), that potentially bind to EV71 and facilitate its entry and infection (Canton et al., 2013; Dang et al., 2014; Gao et al., 2014).