The genome of the uropathogenic lineage A encoded the type 1 fimbriae FimH among other adhesion factors (AidA-I and yqi encoded adhesions), siderophore (enterobactin and yersiniabactin) transporters and hemin receptors (TonB-system) as well as enterotoxins (senB and vat) and Hemolysin E. Although the lineage B isolates did not cause infection, its genomic content reveals similar virulence factors such as the type 1 fimbriae (fimH), serum survival factors (iss) and iron acquisition (aerobactin synthesis and transport), but no enterotoxins. Here, AIDA is linked to infection.