The clinical characteristics for RA patients who provided their sera were as follows; 4 males and 15 females, age 55.3 ± 4.0 years, ESR 55.9 ± 8.7 mm/h, CRP 3.4 ± 0.8 mg/dl, and rheumatoid factor 111.4 ± 27.7 IU/ml. This evidence concerns the gene CRP and rheumatoid arthritis.