TEX19 and neoplasm: The factors that set neuronal tumours apart from other tumour types are likely to be multifold, however, it is noteworthy that LINE-1 retrotransposition is active in somatic neuronal cells [80]; it is not unreasonable to postulate that TEX19 production in neuronal malignancies could limit LINE-1 transposition events and thus limit the evolutionary capacity of the diseased genome and therefore the aggressiveness of the tumour.