There could be number of reasons for this, not least of which is the heterogeneous nature of TEX19 distribution to distinct tumour regions in the colon tumour samples we analysed (i.e. the RNA-seq data may have been obtained from tumour biopsy regions that may have had limited/no TEX19 expression); given this, we cannot rule out a link between TEX19 expression and cancer progression for colorectal cancers. The gene discussed is TEX19; the disease is colorectal cancer.