Various repressors of apoptosis such as Ilf3, Zmym2, Satb1, Ccl21 and Scd were downregulated and expression levels of inducers of apoptosis such as Daxx, Oas1, Lcn2 and Gng2 were upregulated with V3000 infection at 24 h pi resulting in an overall activation of the apoptotic pathway (Fig. 6). The gene discussed is LCN2; the disease is infection.