FADS1 and colorectal carcinoma: In contrast, carriers of the FADS1 rs174550 T major-allele, the ADRA2A rs10885122 G major-allele, and the SLC30A8 rs11558471 A major-allele had associations with increased CRC risk in obese women (BMI ≥ 30, waist >88 cm for FADS1 carriers; w/h > 0.85 for ADRA2A carriers; and ≥40% calories from fat for SLC30A8 carriers) (Tables 4 and 5, and Additional file 4: Table S4.2).