IDH1R132Hprotein was only detected in the IDH1R132H cell lines, and was overexpressed by 6-fold compared with EV or IDH1WT cell lines, while IDH1WT protein was detected in IDH1WT and IDH1R132H glioblastoma cells and GSCs and was overexpressed 4-fold over endogenous IDH1 (Figure 2A), these were in agreement with previous reports [10, 25]. The gene discussed is IDH1; the disease is glioblastoma.