The results of immunohistochemistry were as follows: TTF-1 +, CK(AE1/AE3) partly +, CK7 partly +, CD68 -, GFAP -, Ki67 70-80%, EMA +, SMA tumor cell -, Desmin -, CEA several + and P53 +. The gene discussed is GFAP; the disease is neoplasm.