To map the immune cell infiltration in low- and high-grade gliomas and to investigate potential correlation to serglycin expression levels we performed immunohistochemistry for CD163+ tumor-associated macrophages (TAMs), MCs (tryptase positive) and tumor-infiltrating CD3+ and CD8+ lymphocytes (TILs) (Figure 3). The gene discussed is SRGN; the disease is central nervous system cancer.