K562 cells, SUP-B15 cells and a Ph+ B-ALL primary sample were treated with CFTRinh-172(150 μM, 24 h), and a Western-blot assay was performed with t-BCR-ABL, p-BCR-ABL, Dvl-2, p-GSK3β, β-catenin and β-actin antibodies. Here, BCR is linked to acute lymphoblastic leukemia.