Next, we investigated other cell lines (diverse melanoma lines [SK-Mel, IGR, WK, and MC], B cell and T cell lymphoma [BJAB and Jurkat], and spontaneously transformed keratinocytes [HaCaT]) for the impact of caspase-10 on CD95L-induced cell death. Here, CASP10 is linked to T-cell non-Hodgkin lymphoma.