FASN and metabolic dysfunction-associated steatotic liver disease: Furthermore, an analysis of dietary history and paired serum and liver tissue from patients with NAFLD and gender, age, and body mass index matched controls revealed a 2–3 fold higher fructose consumption (in the form of HFCS) in NAFLD patients with increased hepatic fructokinase (ketohexokinase, KHK) and fatty acid synthase expression, indicating elevated lipogenesis [38].